Extrapancreatic insulinoma
نویسندگان
چکیده
منابع مشابه
Novel extrapancreatic effects of incretin
The hormonal factors implicated as transmitters of signals from the gut to pancreatic β-cells are referred to as incretins. Gastric inhibitory polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) are incretins. In addition to the insulinotropic effects, we have shown, using the GIP receptor and GLP-1 receptor-deficient mice, that GIP and GLP-1 have direct actions on adipocytes and the kidney, ...
متن کاملINSULINOMA NEW CONCEPTS IN MANAGEMENT
In this report, nine patients with insulinoma who were operated on between 19H5 and I <J<J3 at the Shohada Medical Center affiliated to the Shahid Beheshti University of Medical Sciences in Tehran are presented. There were three males and six females (male to female ratio I :2) and the patients' age ranged from 23 to 60 years old (mean age 37.6 years old). Duration of symptoms was from thr...
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Insulinoma is the most common cause of endogenous hyperinsulinemic hypoglycemia in adults. An alternate etiology, non-insulinoma pancreatogenous hypoglycemia (NIPH), is rare. Clinically, NIPH is characterized by postprandial hyperinsulinemic hypoglycemia, negative 72-h fasts, negative preoperative localization studies for insulinoma and positive selective arterial calcium infusion tests. Histol...
متن کاملEvidence of Extrapancreatic Glucagon Secretion in Man.
Glucagon is believed to be a pancreas-specific hormone, and hyperglucagonemia has been shown to contribute significantly to the hyperglycemic state of patients with diabetes. This hyperglucagonemia has been thought to arise from α-cell insensitivity to suppressive effects of glucose and insulin combined with reduced insulin secretion. We hypothesized that postabsorptive hyperglucagonemia repres...
متن کاملResponse of extrapancreatic glucagon to glycemic changes.
Since the secretion of pancreatic glucagon is largely influenced by changes in the blood glucose level, the response of extrapancreatic glucagon to glycemic changes was investigated in man and dogs. Neither insulin-induced hypoglycemia nor arginine infusion caused a rise in plasma glucagon in two patients with total pancreatectomy, but plasma glucagon increased transiently in one of the two pat...
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ژورنال
عنوان ژورنال: World Journal of Nuclear Medicine
سال: 2020
ISSN: 1450-1147
DOI: 10.4103/wjnm.wjnm_41_19